DrugPath is a free-of-charge database of oncology drugs in development, organized by mechanism of action and pharmaceutical/biotechnology company. This resource is designed for academic research laboratories to identify drugs development programs related to genes of interest, and for technology transfer offices to carefully examine unique, competitive therapeutic pipelines in cancer.
Our dataset is carefully maintained by a research team composed of Texas Tech University System faculty and students. To reduce the chance for error, automated scripts are only used as tools to initially identify potential drugs and drug targets in cancer.
Major features of the DrugPath database include:
- Gene database that is standardized with Gene
- Search by gene target, drug name, and company name
- Search the gene pathway (via collaboration with MiMI)
- Exportable drug and gene target details
- Exportable search results
DrugPath offers the ability to search for drug development programs involving an entire gene pathway, a feature made possible through collaboration with the National Center for Integrative Biomedical Informatics (NCIBI). The Michigan Molecular Interactions database (MiMI) can be found at http://mimi.ncibi.org/
Our pipeline database is part of the unified goal of the Texas Tech HSC Cancer Center
to foster collaborative efforts in adult and pediatric cancer translational research.
C. Patrick Reynolds
(Cancer Center Director)
This project is graciously supported by a grant from the Department of Defense.
Shah ED, Fisch BM, Arceci RJ, Buckley JD, Reaman GH, Sorensen PH, Triche TJ, Reynolds CP. DrugPath: a database for academic investigators to match oncology molecular targets with drugs in development. Cancer Chemotherapy and Pharmacology. 2014: 73(5); 1089-93.